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Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy
RECRUITINGPhase 2Sponsored by Hunan Province Tumor Hospital
Actively Recruiting
PhasePhase 2
SponsorHunan Province Tumor Hospital
Started2022-12-25
Est. completion2025-11-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT05584267
Summary
This is a prospective multicenter clinical study. This study aims to construct an auxiliary decision-making system for lung cancer immunotherapy combined with radiotherapy by fusing three modes of imagomics, clinicopathological features, and molecular pathological features.
Eligibility
Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria: * Age ≥ 18 years of age on day of signing informed consent * Histopathology confirmed non-small cell lung cancer * Asymptomatic brain metastases * EGFR/ALK ROS1 driver gene mutation negative * RECIST 1.1 based available assessment of lesions * ECOG 0-1 * Brain metastases 1-4 * Single lesion ≤4cm Exclusion Criteria: * Patients with contraindication of chemotherapy Pregnant or breast feeding women
Conditions3
CancerLung CancerNon Small Cell Lung Cancer
Interventions1
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Actively Recruiting
PhasePhase 2
SponsorHunan Province Tumor Hospital
Started2022-12-25
Est. completion2025-11-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT05584267