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Trifluridine-tipiracil Clinical Trials

17 actively recruiting trials across 6 locations

Also known as: (choose one combination) : oxalipatin or irinotecan, Bevacizumab, FTD/TPI, FTP/TPI, Irinotecan +3 more

Pipeline

Phase 2: 8Phase 3: 2Phase 1/2: 6

Top Sponsors

  • Sun Yat-sen University2
  • Wangxia LV1
  • UNICANCER1
  • The Methodist Hospital Research Institute1
  • Regeneron Pharmaceuticals1

Indications

  • Cancer17
  • Metastatic Colorectal Cancer6
  • Colorectal Cancer Metastatic2
  • Advanced Solid Tumors2
  • Liver Disease1

Other11 trials

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases
Phase 2
A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab
Phase 1/2
Efficacy and Safety of Trifluridine/Tipiracil Combined With Fufuquitinib for Third-line Treatment of mCRC
Phase 2
Lonsurf® (Trifluridine/Tipiracil) Plus Chemotherapy in Metastatic Colorectal Cancer Prospective Study in Taiwan
N/A
Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer
Phase 2
Regorafenib Combined With TAS-102 Versus Regorafenib Monotherapy in Third or Later Line Therapy of mCRC
Phase 2
Second-line Treatment of Metastatic Colorectal Cancer
Phase 2
Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy
Phase 2
Trifluridine/Tipiracil + Fruquintinib Versus Trifluridine/Tipiracil Alone for Metastatic Oeso-gastric Adenocarcinoma
Phase 3
Trifluridine/Tipiracil Combined With Cetuximab in the Treatment of Third-line and Above RAS/BRAF Wild-type mCRC
Phase 1/2
ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC
Phase 1/2

Scottsdale, Arizona1 trial

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Honor Health

Phase 1/2

Duarte, California1 trial

A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

City of Hope National Medical Center /ID# 267875

Phase 3

Fullerton, California1 trial

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Providence Medical Foundation

Phase 1/2

Los Angeles, California1 trial

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Valkyrie Clinical Trials

Phase 1/2

Cleveland, Ohio1 trial

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

Phase 2

Houston, Texas1 trial

5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer

Houston Methodist Neal Cancer Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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