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Olverembatinib Clinical Trials

11 actively recruiting trials across 2 locations

No change since August 2026

Also known as: 6-MP, Cytarabine, Daunorubicin, Dexamethasone, Methotrexate +5 more

Pipeline

Phase 2: 3Phase 3: 4Phase 1/2: 1

Top Sponsors

  • Ascentage Pharma Group Inc.4
  • Institute of Hematology & Blood Diseases Hospital, China3
  • The First Affiliated Hospital of Soochow University1
  • Peking University People's Hospital1
  • M.D. Anderson Cancer Center1

Indications

  • Cancer11
  • Chronic Myeloid Leukemia3
  • Ph-Like1
  • Leukemia, Lymphoblastic, Acute, Philadelphia-Positive1
  • Ph+ ALL1

Other8 trials

A Study of Olverembatinib in SDH-deficient GIST.
Phase 3
ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL
N/A
Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL
N/A
Newly-diagnosed Pediatric Ph-positive B-ALL Protocol
Phase 3
Olverembatinib for FGFR1-rearranged Neoplasms
Phase 2
Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML
Phase 1/2
The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP
Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALL
Phase 2

Birmingham, Alabama2 trials

A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

Ascentage Investigative Site #1044

Phase 3
Study of Olverembatinib (HQP1351) in Patients With CML-CP

Ascentage Investigative Site #1044

Phase 3

Houston, Texas1 trial

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

MD Anderson Cancer Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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