Methotrexate (MTX) Clinical Trials

5 actively recruiting trials across 2 locations

▲ +1 trial since August 2026

Also known as: Low dose Methotrexate, MTX

Pipeline

Phase 2: 4Phase 4: 1

Top Sponsors

Protalix1
Peking Union Medical College Hospital1
Keio University1
Icahn School of Medicine at Mount Sinai1
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh1

Indications

Arthritis3
Cancer2
Primary Intraocular Lymphoma1
Synovitis of Knee1
Osteo Arthritis of the Knee1

Other3 trials

Changes in MTX-PG Concentrations During Subcutaneous MTX Therapy in Patients With Rheumatoid Arthritis(COSMOS Study)

Phase 4

Role of Methotrexate in Ultrasound Proven Synovitis in Primary Knee OA

Phase 2

ZR-MTX for PIOL Phase II Trial

Phase 2

Little Rock, Arkansas1 trial

A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

Applied Research Center of Arkansas

Phase 2

New York, New York1 trial

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

Ruttenberg Treatment Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.