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Ketamine Clinical Trials

28 actively recruiting trials across 18 locations

Also known as: Ket, Ketalar, Ketamine Hydrochloride, Ketamine hydrochloride (Ketamin Inresa 2 ml), Ketamine+Venlafaxine +1 more

Pipeline

Early 1: 2Phase 1: 5Phase 2: 8Phase 3: 2Phase 4: 4Phase 1/2: 1

Top Sponsors

  • Yale University3
  • RIVER Foundation2
  • Mark Niciu2
  • Icahn School of Medicine at Mount Sinai2
  • VA Office of Research and Development1

Indications

  • Depression22
  • Major Depressive Disorder12
  • Anxiety6
  • Post Traumatic Stress Disorder4
  • Treatment-resistant Depression3

Other6 trials

ACT_for Alcohol Use Disorder and Depression
N/A
Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest
ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression
Phase 4
Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients
Phase 3
Pharmacologic Treatment Augmentation in Chronic Depression
Phase 2
The Effect of Ketamine on Aesthetics and Role for Antidepressant Effects
Phase 1

San Francisco, California2 trials

Effect of Ketamine on Intraoperative Motor Evoked Potentials

University of California, San Francisco

Phase 3
Ketamine for Veterans With Parkinson's Disease

San Francisco VA Medical Center, San Francisco, CA

Phase 2

New Haven, Connecticut2 trials

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Yale University

Phase 1
Imaging SV2A in Mood Disorders

PET Center

N/A

Iowa City, Iowa2 trials

Ketamine Alcohol (in Treatment-Resistant Depression)

University of Iowa Health Care

Phase 2
University of Iowa Interventional Psychiatry Service Patient Registry

University of Iowa Health Care

New York, New York2 trials

Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

Icahn School of Medicine at Mount Sinai

Phase 2
Neural Circuit Effects of Ketamine in Depression

Icahn School of Medicine at Mount Sinai

Phase 4

Los Angeles, California1 trial

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

Early 1

Stanford, California1 trial

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

Department of Psychiatry & Behavioral Sciences

Phase 2

West Haven, Connecticut1 trial

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

VA Connecticut Healthcare System

Phase 2

Atlanta, Georgia1 trial

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

Emory University

Early 1

Kansas City, Kansas1 trial

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

University of Kansas Strawberry Hill Campus

Phase 1

Baltimore, Maryland1 trial

Ketamine for Multiple Sclerosis Fatigue

Johns Hopkins University

Phase 2

Bethesda, Maryland1 trial

Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

National Institutes of Health Clinical Center

Phase 1

Boston, Massachusetts1 trial

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Massachusetts General Hospital

Phase 4

Rochester, Minnesota1 trial

Intravenous Ketamine for Treatment-Resistant Depression

Mayo Clinic in Rochester

Phase 2

Bigfork, Montana1 trial

RIVER At Home Ketamine Protocols

RIVER Foundation

Helena, Montana1 trial

Ketamine Treatment Plans for Chronic Conditions

RIVER Telehealth

Nashville, Tennessee1 trial

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Vanderbilt-Ingram Cancer Center

Phase 1/2

Houston, Texas1 trial

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

Wells Medicine

Phase 1

Lubbock, Texas1 trial

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Texas Tech University Health Sciences Center Lubbock

Phase 4

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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