Depression Clinical Trials in Massachusetts

115 recruiting studies across 1 city

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All Trials in Massachusetts

Phase

Trial	Phase	Sponsor	Dist.
A Study of Brenipatide in Adult Participants With Major Depressive Disorder	Phase 3	Eli Lilly and Company	<1 mi
Brain Connectivity in Depression	N/A	Brigham and Women's Hospital	<1 mi
TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age	—	State University of New York at Buffalo	<1 mi
Digital Single Session Intervention for Youth Mental Health	N/A	Harvard University	<1 mi
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care	N/A	Brigham and Women's Hospital	<1 mi
A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)	Phase 3	Definium Therapeutics US, Inc.	<1 mi
Accelerated TMS for Perinatal Depression	N/A	Brigham and Women's Hospital	<1 mi
RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV	N/A	Boston University	<1 mi
BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study	Phase 2	Massachusetts General Hospital	<1 mi
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder	Phase 2	Syndeio Biosciences, Inc	<1 mi
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder	Early 1	Massachusetts General Hospital	<1 mi
Cannabis, Linked Emotions, and Adolescent Risk Study	N/A	Massachusetts General Hospital	<1 mi
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use	N/A	Massachusetts General Hospital	<1 mi
A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)	—	Janssen Research & Development, LLC	<1 mi
Developing a Peer Support Intervention for Depression in SCD	N/A	Massachusetts General Hospital	<1 mi
Cannabidiol for Reduction of Brain Neuroinflammation	Phase 2	Massachusetts General Hospital	<1 mi
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"	Phase 3	Cybin IRL Limited	<1 mi
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)	N/A	Abbott Medical Devices	<1 mi
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms	Phase 4	Axsome Therapeutics, Inc.	<1 mi
Buspirone and Melatonin for Depression Following Traumatic Brain Injury	Phase 4	Massachusetts General Hospital	<1 mi
Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners	N/A	Massachusetts General Hospital	<1 mi
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab	Phase 2	Massachusetts General Hospital	<1 mi
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)	Phase 3	Neurocrine Biosciences	<1 mi
Deep Brain Stimulation of Treatment-Resistant Bipolar Depression	N/A	Wayne Goodman MD	<1 mi
Targeting Specific Brain Networks to Treat Specific Symptoms in Depression	N/A	Massachusetts General Hospital	<1 mi
Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder	Phase 3	Neumora Therapeutics, Inc.	<1 mi
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)	Phase 2	Autobahn Therapeutics, Inc.	<1 mi
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression	Phase 4	Massachusetts General Hospital	<1 mi
Home-Based tDCS Treatment Of Major Depressive Disorder	N/A	Sooma Medical Inc	<1 mi
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms	Phase 3	Janssen Research & Development, LLC	<1 mi
Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study	N/A	Massachusetts General Hospital	<1 mi
Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment	N/A	Boston Medical Center	<1 mi
Mindfulness-Based fMRI Neurofeedback for Depression	N/A	Columbia University	<1 mi
Improving Preschool Outcomes by Addressing Maternal Depression in Head Start	N/A	Brown University	<1 mi
Preventing Childbirth-Related PTSD With Expressive Writing	N/A	Massachusetts General Hospital	<1 mi
Study on Allopregnanolone and Depression in Women Across the Menopause Transition	N/A	Brigham and Women's Hospital	<1 mi
The Association Between Gut Microbiota Diversity and Postpartum Depression	—	Massachusetts General Hospital	<1 mi
Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services	—	Beth Israel Deaconess Medical Center	<1 mi
A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder	Phase 2	Sirtsei Pharmaceuticals, Inc.	<1 mi
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations	N/A	Massachusetts General Hospital	<1 mi
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa	N/A	Boston University Charles River Campus	<1 mi
Study to Assess the Safety and Effectiveness of NMRA-335140-501	Phase 3	Neumora Therapeutics, Inc.	<1 mi
Neural Mechanisms of Family-Focused Treatment for Youth Depression	N/A	Boston University Charles River Campus	<1 mi
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)	Phase 3	Xenon Pharmaceuticals Inc.	<1 mi
Clinical Validation of Samsung Smartwatch	—	Massachusetts General Hospital	<1 mi
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)	Phase 3	Neurocrine Biosciences	<1 mi
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)	Phase 3	Neurocrine Biosciences	<1 mi
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression	N/A	LivaNova	<1 mi
Preventing Depression of Chinese American Adolescents by RRE	N/A	Northeastern University	<1 mi
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder	Phase 3	Xenon Pharmaceuticals Inc.	<1 mi
Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression	N/A	Massachusetts General Hospital	<1 mi
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33	N/A	NYU Langone Health	<1 mi
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool	Phase 3	Senseye, Inc.	<1 mi
The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity	N/A	VA Office of Research and Development	<1 mi
Expressive Writing on Minority Stressors Among Sexual Minority Veterans	N/A	VA Office of Research and Development	<1 mi
Mobile Mental Health Stigma Reduction Intervention Among Black Adults	N/A	Massachusetts General Hospital	<1 mi
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions	N/A	Massachusetts General Hospital	<1 mi
Foundational Programs to Combat Clinician Stress	N/A	Lancaster General Hospital	<1 mi
Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries	N/A	Boston Medical Center	<1 mi
Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest	N/A	Massachusetts General Hospital	<1 mi
Building Connections	N/A	Massachusetts General Hospital	<1 mi
Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency	Phase 1	Elizabeth Austen Lawson	<1 mi
Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II	N/A	Brigham and Women's Hospital	<1 mi
Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health	N/A	Beth Israel Deaconess Medical Center	<1 mi
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV	Phase 2	Massachusetts General Hospital	<1 mi
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)	Phase 2	Seaport Therapeutics	<1 mi
Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression	N/A	Albert Einstein College of Medicine	<1 mi
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness	Phase 2	Brigham and Women's Hospital	<1 mi
Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness	N/A	Massachusetts General Hospital	<1 mi
Modulating Exercise Dosage to Improve Concussion Recovery	Phase 2	University of Colorado, Denver	<1 mi
Positive Minds Strong Joints for Knee Osteoarthritis	N/A	Boston University Charles River Campus	<1 mi
Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study	—	Aura	<1 mi
Training in Evidence-based Treatments in Psycho-Oncology	N/A	Massachusetts General Hospital	<1 mi
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses	Phase 2	Reunion Neuroscience Inc	<1 mi
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder	Phase 3	Sharmin Ghaznavi	1 mi
Researching Heat and Yoga for Mood Enhancement	N/A	Massachusetts General Hospital	3 mi
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone	—	Biogen	3 mi
Testing FIRST in Youth Outpatient Psychotherapy	N/A	Harvard University	3 mi
A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression	Phase 1/2	Juliana Zambrano, MD, MPH	3 mi
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)	Phase 3	Cybin IRL Limited	6 mi
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression	Phase 2	Draig Therapeutics Ltd	6 mi
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)	Phase 2	atai Therapeutics, Inc.	6 mi
Pharmacologic Augmentation of TMS for Depression With D-serine	Phase 1	Mclean Hospital	7 mi
Early Life Stress and Depression: Molecular and Functional Imaging	—	Mclean Hospital	7 mi
Stress Dynamics and Familial Risk for Depression in Female Adolescents	N/A	Mclean Hospital	7 mi
Neural Correlates of Stress and Perceived Control in Adolescent Depression	N/A	Mclean Hospital	7 mi
Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression	—	Mclean Hospital	7 mi
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation	Phase 2	Mclean Hospital	7 mi
Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder	Phase 2	Mclean Hospital	7 mi
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder	Phase 2	Mclean Hospital	7 mi
The Effect of PROSE or Scleral Lenses on Mental Health	—	Boston Sight	10 mi
E-Mindfulness Approaches for Living After Breast Cancer	Phase 3	NRG Oncology	12 mi
BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women	N/A	BTL Industries Ltd.	13 mi
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder	Phase 3	Intra-Cellular Therapies, Inc.	26 mi
Pathways to Perinatal Mental Health Equity	N/A	University of Massachusetts, Worcester	34 mi
A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy	—	Biogen	34 mi
Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients	N/A	Dartmouth-Hitchcock Medical Center	35 mi
Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital	N/A	Massachusetts General Hospital	39 mi
Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in Adults	Phase 2	Autobahn Therapeutics, Inc.	39 mi
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response	Phase 2	ACADIA Pharmaceuticals Inc.	39 mi
Observational Study of THC Concentrations in Acute Cannabis-induced CNS Depression	—	Anebulo Pharmaceuticals	39 mi
A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder	Phase 2	Janssen Research & Development, LLC	39 mi
SAINT in Postpartum Depression (PPD)	N/A	Magnus Medical	39 mi
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder	Phase 2	Syndeio Biosciences, Inc	39 mi
Social Needs Screening and Chronic Diseases Study (WE CARE)	N/A	University of Massachusetts, Worcester	39 mi
Low Intensity Focused Ultrasound: a New Paradigm for Depression and Anxiety	N/A	Ocean State Research Institute, Inc.	41 mi
Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia	N/A	GrayMatters Health Ltd.	41 mi
Collaborative Care Model for Perinatal Wellness Support Services - Population-Level Equity-Centered Systems Change	N/A	Women and Infants Hospital of Rhode Island	41 mi
Testing a Lifestyle Physical Activity Intervention for Women With Depression in Alcohol Treatment	N/A	Butler Hospital	41 mi
Mood and Thought Process Study	N/A	Butler Hospital	41 mi
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers	N/A	Rhode Island Hospital	41 mi
A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior	N/A	Bradley Hospital	41 mi
Supporting Health in Veterans With Heart Failure	N/A	Florida State University	41 mi
Clinical Trial on Agitation in Alzheimer's Dementia	Phase 2	IGC Pharma, LLC	41 mi
Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness	N/A	University of Washington	48 mi

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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